Oncology Platforms And The Promise Of A Cure

By Christina Corridon, Matt Furlow, Caitlin Moore and Matt Lefkowitz

At ZS, the mantra of our oncology work is “Cure it.” Thanks to emerging therapeutic platforms, which we're defining as the confluence of scientific understanding and engineering technology, that mantra is becoming less aspirational and moving closer to becoming a reality. Through variations in the engineering process, a single therapeutic platform can address many different types of cancer.

Our white paper discusses how a deepened understanding of cancer hallmarks and advances in science and engineering have set the stage for emerging therapeutic platforms. We will also reveal where we think these platforms are headed in the future.

We look closer at following platforms which we believe to be the fastest growing in oncology:

• Cell and gene therapy
• Tumor-agnostic development of precision medicine and immuno-oncology therapies
• Bispecific antibodies
• Antibody-drug conjugates
• Therapeutic cancer vaccines and oncolytic viruses
• Radiopharmaceuticals