OCR

WHITE PAPERS AND CASE STUDIES

• Modernizing Operational Maintenance At Treatment Plants

  In 2017, the Harford County Division of Water and Sewer began looking for a modern work management solution to help automate preventive maintenance, coordinate work activities between groups, manage material inventories, and capture important data.

• Developing Amorphous Solid Dispersions For Poorly Soluble Drugs

  Discover how a strategic amorphous solid dispersion approach improved bioavailability and advanced a low-solubility compound toward clinical readiness in just four weeks.

• A Feeder-Free Platform For Generating Mature Natural Killer Cells

  NK cells represent a promising avenue for immunotherapy. Examine the advantages of NK cells in cellular immunotherapy and the importance of developing efficient activation and expansion platforms.

• AAV-Based Gene Editing For Huntington's Disease

  LETI-101 uses AAV5 to deliver a compact CRISPR system for allele-selective editing of mutant HTT, showing promise as a one-time treatment for Huntington’s disease with strong preclinical safety and efficacy.

• Seamless Onshoring From China-Based CDMO

  Successfully mitigate geopolitical risk and maintain supply continuity. Learn how a large-scale manufacturing process was rapidly requalified in eight months to secure a clinical-stage biologic program.

• Early-Stage Development In Rare Pediatric Oncology

  Learn about the strategic approach a biotechnology company utilized to address significant hurdles in launching a Phase 1 clinical trial for a novel therapy targeting a rare pediatric cancer.

• Distortion In High Performance Reflectors

  High-performance optical reflectors, introduce phase effects that cause spatial and temporal distortions. Understanding group delay, and polarization-dependent variations is crucial.

• How To Tackle Water Scarcity In A City Of 22 Million People

  Making Waves spoke with Bing Liu, Sales GM of Xylem’s Water Infrastructure business in China, about the country’s growing water reuse opportunity and one utility leader that is leading the way: Beijing Drainage Group.

• Data Matters: Accelerating Dermatology Research With Precision!

  When deadlines are tight, execution matters. Find out how Palleos delivered critical data packages, statistical analysis, and regulatory-ready documentation—on time and with precision!

• Asset Reinduction To Maximo EAM, Enabled By Reality Capture

  Find out how reality capture was used to create a digital twin 750,000-square-foot Pfizer campus to support asset reinduction to Maximo EAM, saving Pfizer 3,000 hours per year.

• Impact Of Glycosylation On The Effector Functions Of Monoclonal Antibodies

  In an example using rituximab and its biosimilars, explore the significance of minor differences of glycosylation in antibodies and its impact on their properties and functionality.

• Rural Water District Leverages Digital Solutions

  Discover how Qatium seamlessly integrated with RWD4's existing SCADA system, enhancing real-time decision-making and operational insights.